Role of Extracellular Hemoglobin in Thrombosis and Vascular Occlusion in Patients with Sickle Cell Anemia
Sickle cell anemia (SCA) is a common hemolytic disorder caused by a gene mutation in the β-globin subunit of hemoglobin (Hb) and affects millions of people. The intravascular hemolysis releases excessive amount of extracellular hemoglobin (ECHb) into plasma that causes many cellular dysfunctions in...
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Main Authors: | Zhou Zhou, Molly Behymer, Prasenjit Guchhait |
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Format: | Article |
Language: | English |
Published: |
Wiley
2011-01-01
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Series: | Anemia |
Online Access: | http://dx.doi.org/10.1155/2011/918916 |
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