Role of Extracellular Hemoglobin in Thrombosis and Vascular Occlusion in Patients with Sickle Cell Anemia

Sickle cell anemia (SCA) is a common hemolytic disorder caused by a gene mutation in the β-globin subunit of hemoglobin (Hb) and affects millions of people. The intravascular hemolysis releases excessive amount of extracellular hemoglobin (ECHb) into plasma that causes many cellular dysfunctions in...

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Bibliographic Details
Main Authors: Zhou Zhou, Molly Behymer, Prasenjit Guchhait
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Anemia
Online Access:http://dx.doi.org/10.1155/2011/918916
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