Novel pyridine-1,3,4-oxadiazole linked 1,2,3-triazole hybrids: synthesis, molecular docking, ADME, DFT study and anti-tumor potential
Ten novel pyridine-1,3,4-oxadiazole-linked 1,2,3-triazole hybrids (1a-j) were synthesized via a five-step strategy incorporating diverse aromatic substituents with electron-donating and withdrawing groups. Their biological evaluation using the Allium cepa model revealed notable anti-mitotic activity...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-07-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625005041 |
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