The metabolic dialogue between intratumoural microbes and cancer: implications for immunotherapy

The metabolic dialogue between intratumoural microbes and cancer: implications for immunotherapy

Summary: The tumour microenvironment (TME) exerts a profound influence on cancer progression and treatment outcomes. Recent investigations have elucidated the crucial role of intratumoural microbiota and their metabolites in shaping the TME and modulating anti-tumour immunity. This review critically...

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Main Authors: Yingheng Situ, Pengpeng Zhang, Cangang Zhang, Aimin Jiang, Nan Zhang, Lingxuan Zhu, Weiming Mou, Zaoqu Liu, Hank Z.H. Wong, Jian Zhang, Quan Cheng, Anqi Lin, Peng Luo
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:EBioMedicine
Subjects:
Tumour microenvironment
Intratumoural microbiota
Metabolites
Immunotherapy
Immune checkpoint inhibitors
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425001525
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http://www.sciencedirect.com/science/article/pii/S2352396425001525

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