Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies

Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies

Abstract While vaccination against HIV-1 has been so far unsuccessful, recently broadly neutralizing antibodies (bNAbs) against HIV-1 envelope glycoprotein were shown to induce long-term suppression in the absence of antiretroviral therapy in patients with antibody-sensitive viral reservoirs. The re...

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Main Authors: Jord C. Stam, Steven de Maat, Dorien de Jong, Mathia Arens, Fenna van Lint, Lavina Gharu, Mark H. van Roosmalen, Rob C. Roovers, Nika M. Strokappe, Ralf Wagner, Alexander Kliche, Hans J. de Haard, Paul M. van Bergen en Henegouwen, Monique Nijhuis, C. Theo Verrips
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15993-y
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https://doi.org/10.1038/s41598-022-15993-y

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