(Alkyl-ω-ol)triphenyltin(IV)-Loaded Mesoporous Silica as Biocompatible Potential Neuroprotectors: Evaluation of Inhibitory Activity Against Enzymes Associated with the Pathophysiology of Alzheimer’s Disease

(Alkyl-ω-ol)triphenyltin(IV)-Loaded Mesoporous Silica as Biocompatible Potential Neuroprotectors: Evaluation of Inhibitory Activity Against Enzymes Associated with the Pathophysiology of Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by synaptic dysfunction and neuronal loss due to the accumulation of amyloid-β peptides and tau proteins. In the pursuit of novel neuroprotective strategies, organotin(IV) compounds have garnered attention due to thei...

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Bibliographic Details
Main Authors: Kristina Milisavljević, Žiko Milanović, Jovana Matić, Marko Antonijević, Vladimir Simić, Miljan Milošević, Marijana Kosanić, Goran N. Kaluđerović
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Nanomaterials
Subjects:
Alzheimer’s disease
triphenyltin(IV) compounds
mesoporous silica SBA-15
molecular docking
molecular dynamics
computational brain model
Online Access:https://www.mdpi.com/2079-4991/15/12/914
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