CD2AP shapes a stromal reduced tumor microenvironment and contributes to immunotherapy in gastric cancer

CD2AP shapes a stromal reduced tumor microenvironment and contributes to immunotherapy in gastric cancer

Abstract Gastric cancer (GC) ranks as the fifth most prevalent malignant tumor and stands as the fourth leading contributor to cancer-related fatalities on a global scale. The specific link between CD2 Associated Protein (CD2AP) expression and the tumor microenvironment (TME) remains unclear, and fu...

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Main Authors: Haoliang Li, Hua Chen, Ting Zhao, Wenqi Zhang, Jing Deng, Wangkai Xie, Jianing Fan, Han Lou, Pingping Dong, Zheng Han, Dong Xing, Sunzhong Mao, Xian Shen, Xiangyang Xue, Mingdong Lu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
Gastric cancer
Tumor microenvironment
Stromal
Immune cell
Immunotherapy
Online Access:https://doi.org/10.1186/s12885-025-14248-z
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https://doi.org/10.1186/s12885-025-14248-z

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