Interprofessional Therapeutic Drug Monitoring of Piperacillin/Tazobactam Enhances Care for Patients with Acute-on-Chronic Liver Failure in the ICU: A Retrospective Observational Pilot Study

Interprofessional Therapeutic Drug Monitoring of Piperacillin/Tazobactam Enhances Care for Patients with Acute-on-Chronic Liver Failure in the ICU: A Retrospective Observational Pilot Study

<b>Background:</b> Acute-on-chronic liver failure (ACLF) is a severe, rapidly progressing syndrome in patients with liver cirrhosis, often triggered by bacterial infections. Piperacillin/Tazobactam is a key antibiotic in this setting, and therapeutic drug monitoring (TDM) helps optimize...

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Main Authors: Stephan Schmid, Katharina Zimmermann, Chiara Koch, Patricia Mester, Georgios Athanasoulas, Jonas Buttenschoen, Daniel Fleischmann, Sophie Schlosser-Hupf, Vlad Pavel, Tobias Schilling, Martina Müller, Alexander Kratzer
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Antibiotics
Subjects:
therapeutic drug monitoring (TDM)
piperacillin/tazobactam
intensive care unit
interprofessional collaboration
acute-on-chronic liver failure
Online Access:https://www.mdpi.com/2079-6382/14/2/202
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https://www.mdpi.com/2079-6382/14/2/202

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