Lung‐delivered IL‐10 mitigates Lung inflammation induced by repeated endotoxin exposures in male mice

Lung‐delivered IL‐10 mitigates Lung inflammation induced by repeated endotoxin exposures in male mice

Abstract Therapies capable of resolving inflammatory lung disease resulting from high‐consequence occupational/environmental hazards are lacking. This study seeks to determine the therapeutic potential of direct lung‐delivered interleukin (IL)‐10 following repeated lipopolysaccharide exposures. C57B...

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Main Authors: Aaron D. Schwab, Todd A. Wyatt, Oliver W. Schanze, Amy J. Nelson, Angela M. Gleason, Michael J. Duryee, Deanna D. Mosley, Geoffrey M. Thiele, Ted R. Mikuls, Jill A. Poole
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Physiological Reports
Subjects:
endotoxin
environmental lung disease
inflammation
macrophages
occupational
Online Access:https://doi.org/10.14814/phy2.70253
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https://doi.org/10.14814/phy2.70253

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