A novel outer membrane vesicle adjuvant improves vaccine protection against Bordetella pertussis

Abstract Pertussis is a vaccine-preventable respiratory disease caused by the Gram negative coccobacillus Bordetella pertussis. The licensed acellular pertussis (aP) vaccines protect against disease but do not prevent bacterial colonization and transmission. Here, we developed and tested an intranas...

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Bibliographic Details
Main Authors: Michelle Galeas-Pena, Allyson Hirsch, Erin Kuang, Joseph Hoffmann, Patrick Gellings, Jasmine B. Brown, Vanessa M. Limbert, Claire L. Callahan, James B. McLachlan, Lisa A. Morici
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00990-1
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