Correlation of lymphocyte-to-monocyte, platelet-to-lymphocyte, and neutrophil-to-lymphocyte ratios with skin-symptom improvement following antimicrobial treatment in palmoplantar pustulosis

Correlation of lymphocyte-to-monocyte, platelet-to-lymphocyte, and neutrophil-to-lymphocyte ratios with skin-symptom improvement following antimicrobial treatment in palmoplantar pustulosis

Abstract Background Palmoplantar Pustulosis (PPP) is a chronic inflammatory skin disease that presents as pustules on the palms and soles. There are no oral medications for patients with mild PPP, with apremilast, a new oral PDE4 inhibitor, indicated for moderate to severe cases of the disease. We p...

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Main Authors: Kuninori Iwayama, Takayuki Manabe, Ko-Ichi Ohtaki, Masayuki Chuma, Mari Kishibe, Masaru Honma, Yoshikazu Tasaki
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Palmoplantar pustulosis
Antimicrobial drug treatment
Lymphocyte-to-monocyte ratio
Blood count indicator
Monitoring.
Online Access:https://doi.org/10.1186/s40780-025-00479-6
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https://doi.org/10.1186/s40780-025-00479-6

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