Metformin-Induced Apoptosis Is Mediated Through Mitochondrial VDAC1

Metformin-Induced Apoptosis Is Mediated Through Mitochondrial VDAC1

<b>Background:</b> Besides diabetes mellitus, metformin has been identified as a potential therapeutic agent for treating various other conditions that include various cancers, cardiovascular diseases, neurodegenerative diseases, and aging. In cancer, metformin increased apoptotic cell d...

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Bibliographic Details
Main Authors: Anna Shteinfer-Kuzmine, Meital M. Moyal, Aditya Karunanithi Nivedita, Sweta Trishna, Almog Nadir, Shubhandra Tripathi, Varda Shoshan-Barmatz
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceuticals
Subjects:
apoptosis
hexokinase
metformin
mitochondria
VDAC1
Online Access:https://www.mdpi.com/1424-8247/18/5/757
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