Impact of Tregs on tumor regression in locally advanced G/GEJ cancer patients undergoing neoadjuvant chemoimmunotherapy

Impact of Tregs on tumor regression in locally advanced G/GEJ cancer patients undergoing neoadjuvant chemoimmunotherapy

Abstract Neoadjuvant chemoimmunotherapy has transformed the treatment of locally advanced gastric or gastroesophageal junction (G/GEJ) cancer. However, identifying reliable predictive markers for treatment efficacy remains challenging. We conducted a retrospective analysis to evaluate the prognostic...

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Bibliographic Details
Main Authors:	Yong Zhang, Chaoji Zhang, Peng Qin, Baozhen Ma, Anqi Lyu, Fang Zhang, Tiepeng Li, Lu Han, Yiman Shang, Zibing Wang, Quanli Gao, Lingdi Zhao
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Series:	Scientific Reports
Subjects:	Neoadjuvant chemoimmunotherapy Gastric or gastroesophageal junction cancer Regulatory T cells Predictive markers Personalized treatment
Online Access:	https://doi.org/10.1038/s41598-025-14110-z
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