Bioenergetic-related gene expression in the hippocampus predicts internalizing vs. externalizing behavior in an animal model of temperament

Bioenergetic-related gene expression in the hippocampus predicts internalizing vs. externalizing behavior in an animal model of temperament

Externalizing and internalizing behavioral tendencies underlie many psychiatric and substance use disorders. These tendencies are associated with differences in temperament that emerge early in development via the interplay of genetic and environmental factors. To better understand the neurobiology...

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Bibliographic Details
Main Authors: Elaine K. Hebda-Bauer, Megan H. Hagenauer, Daniel B. Munro, Peter Blandino, Fan Meng, Keiko Arakawa, John D. H. Stead, Apurva S. Chitre, A. Bilge Ozel, Pejman Mohammadi, Stanley J. Watson, Shelly B. Flagel, Jun Li, Abraham A. Palmer, Huda Akil
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
temperament
hippocampus
RNA-Seq
locomotor activity
anxiety
energy metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2025.1469467/full
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https://www.frontiersin.org/articles/10.3389/fnmol.2025.1469467/full

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