Liquid Chromatography/Tandem Mass Spectrometry Method for Quantitation of Cremophor EL and Its Applications

A rapid sensitive and selective MRM based method for the determination of Cremophor EL (CrEL) in rat plasma was developed using liquid chromatography/tandem mass spectrometry (LC-MS/MS). CrEL and polypropylene glycol (internal standard) were extracted from rat plasma with acetonitrile and analysed o...

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Bibliographic Details
Main Authors: V. Vijaya Bhaskar, Anil Middha
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2013/135613
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