An extension of the Spiegelhalter-Knill-Jones method for continuous covariates in clinical decision making

An extension of the Spiegelhalter-Knill-Jones method for continuous covariates in clinical decision making

Abstract Background There is still demand for algorithms that can be used at the point of care, especially when dealing with events that do not present with a single obvious clinical indicator. The Spiegelhalter-Knill-Jones (SKJ) method is an approach for the development of a clinical score that foc...

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Bibliographic Details
Main Authors: Bart K. M. Jacobs, Tafadzwa Maseko, Lutgarde Lynen, Aquiles Rodrigo Henriquez-Trujillo, Jozefien Buyze
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Medical Research Methodology
Subjects:
Prediction
Likelihood ratio
Clinical decision making
Threshold
Scoring algorithm
Generalised additive model
Online Access:https://doi.org/10.1186/s12874-025-02591-5
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https://doi.org/10.1186/s12874-025-02591-5

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