Navigating cross-reactivity and host species effects in a serological assay: A case study of the microscopic agglutination test for Leptospira serology.

<h4>Background</h4>Serology (the detection of antibodies formed by the host against an infecting pathogen) is frequently used to assess current infections and past exposure to specific pathogens. However, the presence of cross-reactivity among host antibodies in serological data makes it...

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Bibliographic Details
Main Authors: Riley O Mummah, Ana C R Gomez, Angela H Guglielmino, Benny Borremans, Renee L Galloway, Katherine C Prager, James O Lloyd-Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0012042
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