Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

Chemotherapy is widely used to treat lung adenocarcinoma (LUAD) patients comprehensively. Considering the limitations of chemotherapy due to drug resistance and other issues, it is crucial to explore the impact of chemotherapy and immunotherapy on these aspects. In this study, tumor samples from nin...

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Main Authors: Yiwei Huang, Gujie Wu, Guoshu Bi, Lin Cheng, Jiaqi Liang, Ming Li, Huan Zhang, Guangyao Shan, Zhengyang Hu, Zhencong Chen, Zongwu Lin, Wei Jiang, Qun Wang, Junjie Xi, Shanye Yin, Cheng Zhan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
lung adenocarcinoma
neoadjuvant chemotherapy
phenotype atlas
metabolic reprogramming
Online Access:https://elifesciences.org/articles/95988
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https://elifesciences.org/articles/95988

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