Activation of the aryl hydrocarbon receptor with structurally diverse ligands suppresses class switch to immunoglobulin A

Abstract Objective Activation of the aryl hydrocarbon receptor (AhR) with its prototypical agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppresses B cell class switch recombination (CSR). In T cells, AhR activation with structurally diverse agonists has been reported to alter differentiation n...

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Bibliographic Details
Main Authors: Alex B. Costa, Gregory K. DeKrey
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Research Notes
Subjects:
Online Access:https://doi.org/10.1186/s13104-025-07364-3
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