Progression of chronic wasting disease in white-tailed deer analyzed by serial biopsy RT-QuIC and immunohistochemistry.

Progression of chronic wasting disease in white-tailed deer analyzed by serial biopsy RT-QuIC and immunohistochemistry.

Chronic wasting disease (CWD) continues to spread or be recognized in the United States, Canada, and Europe. CWD is diagnosed by demonstration of the causative misfolded prion protein (PrPCWD) in either brain or lymphoid tissue using immunodetection methods, with immunohistochemistry (IHC) recognize...

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Bibliographic Details
Main Authors: Davin M Henderson, Nathaniel D Denkers, Clare E Hoover, Erin E McNulty, Sarah K Cooper, Lauren A Bracchi, Candace K Mathiason, Edward A Hoover
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0228327/1/pone.0228327.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210218%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210218T134628Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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