Spleen volume in relation to ulcerative colitis and Crohn’s disease: a Mendelian randomization study

Spleen volume in relation to ulcerative colitis and Crohn’s disease: a Mendelian randomization study

Abstract Prior research has established the significance of spleen volume (SV) in the pathogenesis and advancement of ulcerative colitis (UC) and Crohn’s disease (CD). Nevertheless, these investigations are predominantly observational, thereby leaving their causal associations ambiguous. Moreover, t...

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Bibliographic Details
Main Authors: Qiang Su, Jian Li, Yun Lu, Jiang Liang, Song Huang, Min Wu, Yuanli He, Zhenxiang An, Jinbing Ding, Zhizhong Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Mendelian randomization
Spleen volume
Inflammatory bowel disease
Genetic association
Instrumental variables
Ulcerative colitis
Online Access:https://doi.org/10.1038/s41598-025-90104-1
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https://doi.org/10.1038/s41598-025-90104-1

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