Posterior cingulate cortex downregulation training using fMRI neurofeedback in adolescents with early life adversity exposure: a randomized, single-blind trial

Posterior cingulate cortex downregulation training using fMRI neurofeedback in adolescents with early life adversity exposure: a randomized, single-blind trial

Abstract Early life adversity (ELA) disrupts default mode network (DMN) integrity subserving self-referential processes involved in emotional awareness and regulation. Mindfulness training (MT) reduces self-referential processing and down-regulates the DMN. We employed neurofeedback-augmented mindfu...

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Main Authors: Xiaoqian Yu, Aki Tsuchiyagaito, Masaya Misaki, Gabe Cochran, Zsofia P. Cohen, Manpreet K. Singh, Martin P. Paulus, Robin L. Aupperle, Namik Kirlic
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03445-w
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https://doi.org/10.1038/s41398-025-03445-w

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