Identification of m5C RNA modification-related gene signature for predicting prognosis and immune microenvironment-related characteristics of heart failure

Identification of m5C RNA modification-related gene signature for predicting prognosis and immune microenvironment-related characteristics of heart failure

Abstract Background Methylation of RNA is involved in many pathophysiological processes. The roles of N6-methyladenosine (m6A) and N7-methylguanosine (m7G) in heart failure (HF) have been established. However, the impact of 5-methylcytosine (m5C) on HF and its relationship with the immune microenvir...

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Main Authors: Zirui Liu, Rui Feng, Ying Xu, Meili Liu, Haocheng Wang, Yu Lu, Weiqi Wang, Jikai Wang, Cao Zou
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Hereditas
Subjects:
m5C
RNA methylation
Heart failure
Bioinformatic analysis
Online Access:https://doi.org/10.1186/s41065-025-00454-z
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https://doi.org/10.1186/s41065-025-00454-z

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