Tissue plasminogen activator modified thromboelastography identifies fibrinolysis resistance in dogs with immune-mediated hemolytic anemia

Tissue plasminogen activator modified thromboelastography identifies fibrinolysis resistance in dogs with immune-mediated hemolytic anemia

IntroductionImmune-mediated hemolytic anemia (IMHA) is an important immunologic disorder in dogs that is associated with high mortality rates, frequently due to thromboembolism. Multiple factors contribute to the pathophysiology of thrombosis in IMHA including intravascular tissue factor expression,...

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Bibliographic Details
Main Authors: Robert Goggs, Samantha Davis, Marjory B. Brooks
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Veterinary Science
Subjects:
immunothrombosis
neutrophil extracellular traps
nucleosomes
cell-free DNA
thrombin-activatable fibrinolysis inhibitor
plasminogen activator inhibitor-1
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1571683/full
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https://www.frontiersin.org/articles/10.3389/fvets.2025.1571683/full

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