Development of a Recombinant Outer Membrane Vesicles (OMVs)‐Based Vaccine Against Helicobacter pylori Infection in Mice

Development of a Recombinant Outer Membrane Vesicles (OMVs)‐Based Vaccine Against Helicobacter pylori Infection in Mice

ABSTRACT The current vaccine development for Helicobacter pylori (H. pylori) still faces challenges of weak immune responses stimulated by existing antigens and a lack of safe adjuvants. The modification of the lipopolysaccharide (LPS) structure by H. pylori is an important mechanism involved in its...

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Main Authors: Qiong Liu, Biaoxian Li, Jinrong Ma, Xiao Lei, Junpeng Ma, Yanyan Da, Zhiyong Zhou, Jiaqi Tao, Xinyi Ren, Ting Zeng, Zhiting Xie, Haiyan Lin, Zihui Jin, Yi Wan, Liang Zhang, Donglin Lai, Yaping Guo, Jing Li, Yinpan Shang, Lu Shen, Ziwei Tao, Tian Gong, Chengsheng Zhang
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Journal of Extracellular Vesicles
Subjects:
H. pylori
LPS
OMVs
recombinant vaccine
Online Access:https://doi.org/10.1002/jev2.70085
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https://doi.org/10.1002/jev2.70085

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