Enhanced Expression of TRIM46 in Ovarian Cancer Cells Induced by Tumor-Associated Macrophages Promotes Invasion via the Wnt/β-Catenin Pathway

Enhanced Expression of TRIM46 in Ovarian Cancer Cells Induced by Tumor-Associated Macrophages Promotes Invasion via the Wnt/β-Catenin Pathway

Metastasis presents significant challenges in ovarian cancer treatment. Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) facilitate metastasis through epithelial-mesenchymal transition, yet the molecular underlying mechanisms are not fully understood. Here, we identified t...

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Bibliographic Details
Main Authors: Yi-Yue Wang, Min-Jun Choi, Jin-Hyung Kim, Jung-Hye Choi
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Cells
Subjects:
tumor-associated macrophages
ovarian cancer
invasion
TRIM46
Wnt/β-catenin
Online Access:https://www.mdpi.com/2073-4409/14/3/214
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