Stability and Efficacy of Mucoadhesive Eye Drops Containing Olopatadine HCl: Physicochemical, Functional, and Preclinical In Vivo Assessment

Stability and Efficacy of Mucoadhesive Eye Drops Containing Olopatadine HCl: Physicochemical, Functional, and Preclinical In Vivo Assessment

<b>Background:</b> The incorporation of polymers into drug delivery vehicles has been shown to be an effective strategy to prolong the residence time of active ingredients in the precorneal tear film and to increase ocular bioavailability. <b>Objectives:</b> The aim of this s...

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Bibliographic Details
Main Authors: Anđelka Račić, Veljko Krstonošić, Ana Micov, Uroš Pecikoza, Vladimir Dobričić, Erna Turković, Danina Krajišnik
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
Subjects:
olopatadine hydrochloride
hydroxypropyl guar gum
sodium hyaluronate
eye drops
rheological synergism
mucoadhesivity
Online Access:https://www.mdpi.com/1999-4923/17/4/517
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