Unraveling the Role of METTL3 in Helicobacter pylori-induced gastritis via m6A-CXCL1/NF-κB modulation

Abstract Helicobacter pylori (H. pylori) infection is a significant cause of gastric diseases, with its pathogenic mechanisms still not fully understood. This study investigates the role of METTL3, an enzyme involved in m6A methylation, in modulating the CXCL1/NF-κB signaling pathway in H. pylori-in...

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Bibliographic Details
Main Authors: Qiutong Lu, Zhaopeng Wang, Shuixian Cao, Huan Wang, Nianshuang Li, Yi Hu, Wuhui Ding, Wei Zuo, Junbo Hong
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07841-4
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