Periodic leg movements and cognitive function in middle-aged and elderly adults with mediating role of REM duration and PLMS-related arousal

Abstract The relationship between periodic leg movements of sleep (PLMS) and cognitive function is controversial. This study aims to explore: (1) the effects of PLMS on cognitive function in middle-aged and elderly patients; and (2) the mediating role of rapid eye movement (REM) sleep duration and P...

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Bibliographic Details
Main Authors: Shutong Sun, Liwen Xu, Yixi Zheng, Wenyi Yu, Tianyu Jing, Gang Xu, Tieyu Tang, Cheng Chu
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-04660-7
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