Transposition element MERVL regulates DNA demethylation through TET3 in oxidative-damaged mouse preimplantation embryos

Abstract Transposable elements (TEs) comprise approximately half of eukaryotic genomes and significantly contribute to genome plasticity. In this study, we focused on a specific TE, MERVL, which exhibits particular expression during the 2-cell stage and commonly serves as an indicator of embryonic t...

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Bibliographic Details
Main Authors: Lihong Liu, Siyao Ha, Dan Cao, MingQing Li, Zhiling Li
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-025-01143-3
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