Discovery of Lithospermate B as a Potential Ligand for the Malarial E2 Ubiquitin-Conjugating Enzyme via Multiplexed Native Mass Spectrometry

There is an urgent need for novel therapeutics to combat <i>Plasmodium falciparum</i>, especially in light of increasing drug resistance. Here, we present a multiplexed native mass spectrometry (MS) platform capable of simultaneously screening multiple protein targets against chemically...

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Bibliographic Details
Main Authors: Jianying Han, Wesley C. Van Voorhis, Ronald J. Quinn, Miaomiao Liu
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Chemosensors
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Online Access:https://www.mdpi.com/2227-9040/13/5/166
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