Putative and pretreatment drug resistance mutations in reverse transcriptase gene among untreated chronic hepatitis B patients at Arifin Achmad Regional District Hospital, Riau, Indonesia

Putative and pretreatment drug resistance mutations in reverse transcriptase gene among untreated chronic hepatitis B patients at Arifin Achmad Regional District Hospital, Riau, Indonesia

Background: Mutations within the hepatitis B virus (HBV) reverse transcriptase (RT) gene have been associated with drug resistance against nucleos(t)ide analogs (NAs). Objective: This study aimed to identify mutations in the RT gene among patients with chronic hepatitis B (CHB) before receiving...

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Main Authors: Arfianti Arfianti, Fauzia Andrini Djojosugito, Maisaroh Maisaroh, Hendra Asputra, Dita Kartika Sari, Tubagus Odih Rhomdani Wahid
Format: Article
Language:English
Published: Indonesian Society for Biochemistry and Molecular Biology 2022-05-01
Series:Acta Biochimica Indonesiana
Subjects:
chronic hepatitis B
genitype
nucleos(t)ide analogues
reverse transcriptase
resistance muation
Online Access:https://pbbmi.org/newjurnal/index.php/actabioina/article/view/68
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