Nucleoprotein S69 phosphorylation regulates influenza A virus replication

Abstract Phosphorylation of the influenza A virus (IAV) nucleoprotein (NP) is crucial for the viral life cycle, as it encapsidates the viral genomic RNA. Here, we employed mass spectrometry to identify serine 69 (S69) as a novel phosphorylation site of NP in IAV. Sequence homology alignment revealed...

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Bibliographic Details
Main Authors: Yun Li, Pengtao Jiao, Weinan Zheng, Wenjun Liu, Lei Sun
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Animal Diseases
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Online Access:https://doi.org/10.1186/s44149-025-00184-9
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