The Primary Responses of Murine Neonatal Lymph Node CD4+ Cells are Th2-skewed and are Sufficient for the Development of Th2-biased Memory

Exposure of neonatal mice to antigen often results in Th2-biased responses in later life. Examples of this Th2 tendency are (a) secondary antibody responses dominated by the Th2-associated IgG1 isotype and (b) Th2-mediated tolerance to alloantigens. We previously reported that neonates develop prima...

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Bibliographic Details
Main Authors: Becky Adkins, Yurong Bu, Vladimir Vincek, Patricia Guevara
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1080/10446670310001598474
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