Efficacy and safety of immunotherapy or antiangiogenic agent-based treatment strategies versus chemotherapy as first-line treatment for extensive-stage small cell lung cancer: a network meta-analysis

Efficacy and safety of immunotherapy or antiangiogenic agent-based treatment strategies versus chemotherapy as first-line treatment for extensive-stage small cell lung cancer: a network meta-analysis

ObjectiveImmune checkpoint inhibitors (ICIs) combined with etoposide-platinum are recommended as the standard first-line therapy for extensive-stage small cell lung cancer (ES-SCLC). Despite the potential of antiangiogenic agents to enhance treatment efficacy, the optimal combination pattern remains...

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Bibliographic Details
Main Authors: Chengjun Wang, Chuang Yang, Wen Zhao, Rongyu Zhang, Tiantian Xuan, Jisheng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
small cell lung cancer
immunotherapy
antiangiogenesis
network meta-analysis
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1539246/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1539246/full

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