Activation of TLR4/CCL2 in Intact Neurons Drives Radicular Injury-Induced Global Nerve Trunk Hypersensitivity in Radiculopathy Preclinical Models

Activation of TLR4/CCL2 in Intact Neurons Drives Radicular Injury-Induced Global Nerve Trunk Hypersensitivity in Radiculopathy Preclinical Models

Si-Han Tong,1,2,* Jian Zhou,1,2,* Fang Ye,3,* Peng Ding,1,2 Jia-Lun Mei,1,2 Peng Liao,4 Ya-Fei Lu,1,2 Yao Zong,5 Chu-An Gao,1,2 Sen-Yao Zhang,1,2 Jun-Jie Gao,1,2 De-Lin Liu,1,2 Yi-Gang Huang1 1Department of Orthopaedics, Shanghai Sixth People’s Hospital Affiliated...

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Bibliographic Details
Main Authors: Tong SH, Zhou J, Ye F, Ding P, Mei JL, Liao P, Lu YF, Zong Y, Gao CA, Zhang SY, Gao JJ, Liu DL, Huang YG
Format: Article
Language:English
Published: Dove Medical Press 2025-08-01
Series:Journal of Pain Research
Subjects:
Painful radiculopathy
nerve trunk hypersensitivity
uninjured neuron
CCL2
TLR4
Online Access:https://www.dovepress.com/activation-of-tlr4ccl2-in-intact-neurons-drives-radicular-injury-induc-peer-reviewed-fulltext-article-JPR
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https://www.dovepress.com/activation-of-tlr4ccl2-in-intact-neurons-drives-radicular-injury-induc-peer-reviewed-fulltext-article-JPR

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