Microstructural abnormalities in multiple system atrophy as revealed by conventional and rotating frame relaxation MRI parameters

Microstructural abnormalities in multiple system atrophy as revealed by conventional and rotating frame relaxation MRI parameters

Abstract Rotating frame relaxation (RFR) techniques provide robust and sensitive quantitative MRI (qMRI) metrics able to detect subtle alterations of brain tissue integrity in multiple neurological disorders. We performed a cross-sectional qMRI study in 16 patients with Multiple System Atrophy (MSA)...

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Main Authors: Antonietta Canna, Silvia Mangia, Shalom Michaeli, Sara Ponticorvo, Maria Claudia Russillo, Valentina Andreozzi, Renzo Manara, Francesco Di Salle, Marina Picillo, Paolo Barone, Fabrizio Esposito, Maria Teresa Pellecchia
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Adiabatic T1ρ
T2ρ
MT
R1
R2*
MSA
Online Access:https://doi.org/10.1038/s41598-025-10812-6
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https://doi.org/10.1038/s41598-025-10812-6

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