Humanized COVID‐19 decoy antibody effectively blocks viral entry and prevents SARS‐CoV‐2 infection

Humanized COVID‐19 decoy antibody effectively blocks viral entry and prevents SARS‐CoV‐2 infection

Abstract To circumvent the devastating pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, a humanized decoy antibody (ACE2‐Fc fusion protein) was designed to target the interaction between viral spike protein and its cellular receptor, angiotensin‐converting e...

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Bibliographic Details
Main Authors: Kuo‐Yen Huang, Ming‐Shiu Lin, Ting‐Chun Kuo, Ci‐Ling Chen, Chung‐Chih Lin, Yu‐Chi Chou, Tai‐Ling Chao, Yu‐Hao Pang, Han‐Chieh Kao, Rih‐Sheng Huang, Steven Lin, Sui‐Yuan Chang, Pan‐Chyr Yang
Format: Article
Language:English
Published: Springer Nature 2020-11-01
Series:EMBO Molecular Medicine
Subjects:
ACE2‐Fc
COVID‐19
decoy antibody
SARS‐CoV‐2
virus infection
Online Access:https://doi.org/10.15252/emmm.202012828
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https://doi.org/10.15252/emmm.202012828

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