Association between coffee and caffeine consumption and chronic kidney disease
Abstract Chronic kidney disease (CKD) is a significant global health issue associated with cardiovascular complications. While coffee, tea, and caffeine consumption have been linked to various health benefits, their relationship with CKD remains unclear. We conducted a cross-sectional analysis of NH...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-11543-4 |
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| author | Panpan Gao Xinrong Ji Weiwei Wang Yao Chen Zhan Gao Zengli Yu |
| author_facet | Panpan Gao Xinrong Ji Weiwei Wang Yao Chen Zhan Gao Zengli Yu |
| author_sort | Panpan Gao |
| collection | DOAJ |
| description | Abstract Chronic kidney disease (CKD) is a significant global health issue associated with cardiovascular complications. While coffee, tea, and caffeine consumption have been linked to various health benefits, their relationship with CKD remains unclear. We conducted a cross-sectional analysis of NHANES 1999–2018 data, including 49,827 participants, assessing dietary intake through two 24-hour recalls and determining CKD status via the CKD-EPI equation. Our results showed that after adjusting for covariates, higher coffee consumption (> 352.5 g/day) was associated with lower odds of CKD (OR 0.760, 95% CI 0.701–0.823), as was tea consumption (OR 0.913, 95% CI 0.843–0.89). The highest tertile of caffeine consumption also showed a significantly reduced odds of CKD (OR 0.734, 95% CI 0.674–0.799). These findings suggest that coffee, tea, and caffeine consumption may be associated with better renal function, highlighting potential dietary strategies for CKD prevention. |
| format | Article |
| id | doaj-art-fdf95d53d65f4ea1a9a680861fbca290 |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-fdf95d53d65f4ea1a9a680861fbca2902025-08-20T03:05:21ZengNature PortfolioScientific Reports2045-23222025-07-0115111010.1038/s41598-025-11543-4Association between coffee and caffeine consumption and chronic kidney diseasePanpan Gao0Xinrong Ji1Weiwei Wang2Yao Chen3Zhan Gao4Zengli Yu5The Third Hospital affiliated Zhengzhou UniversityThe Fifth Hospital affiliated Zhengzhou UniversityThe Fifth Hospital affiliated Zhengzhou UniversityThe Fifth Hospital affiliated Zhengzhou UniversityThe Fifth Hospital affiliated Zhengzhou UniversityThe Third Hospital affiliated Zhengzhou UniversityAbstract Chronic kidney disease (CKD) is a significant global health issue associated with cardiovascular complications. While coffee, tea, and caffeine consumption have been linked to various health benefits, their relationship with CKD remains unclear. We conducted a cross-sectional analysis of NHANES 1999–2018 data, including 49,827 participants, assessing dietary intake through two 24-hour recalls and determining CKD status via the CKD-EPI equation. Our results showed that after adjusting for covariates, higher coffee consumption (> 352.5 g/day) was associated with lower odds of CKD (OR 0.760, 95% CI 0.701–0.823), as was tea consumption (OR 0.913, 95% CI 0.843–0.89). The highest tertile of caffeine consumption also showed a significantly reduced odds of CKD (OR 0.734, 95% CI 0.674–0.799). These findings suggest that coffee, tea, and caffeine consumption may be associated with better renal function, highlighting potential dietary strategies for CKD prevention.https://doi.org/10.1038/s41598-025-11543-4CoffeeTeaCaffeineChronic kidney diseaseNHANES |
| spellingShingle | Panpan Gao Xinrong Ji Weiwei Wang Yao Chen Zhan Gao Zengli Yu Association between coffee and caffeine consumption and chronic kidney disease Scientific Reports Coffee Tea Caffeine Chronic kidney disease NHANES |
| title | Association between coffee and caffeine consumption and chronic kidney disease |
| title_full | Association between coffee and caffeine consumption and chronic kidney disease |
| title_fullStr | Association between coffee and caffeine consumption and chronic kidney disease |
| title_full_unstemmed | Association between coffee and caffeine consumption and chronic kidney disease |
| title_short | Association between coffee and caffeine consumption and chronic kidney disease |
| title_sort | association between coffee and caffeine consumption and chronic kidney disease |
| topic | Coffee Tea Caffeine Chronic kidney disease NHANES |
| url | https://doi.org/10.1038/s41598-025-11543-4 |
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