PLASTY OF DURA MATER DEFECTS BY COLLAGEN IMPLANTS USING NON-SUTURE CONTACT DIRECT BONDING METHOD

OBJECTIVE. The study investigated and compared the efficacy of plasty of dura mater using different collagen materials in the experiment. MATERIALS AND METHODS. The experimental study in vivo was carried out on 60 laboratory animals. Rabbits were divided into 4 groups after performing the craniotomy...

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Main Authors: D. E. Alekseev, D. V. Svistov, D. E. Matsko, E. D. Alekseev
Format: Article
Language:Russian
Published: Pavlov First Saint Petersburg State Medical University 2017-04-01
Series:Вестник хирургии имени И.И. Грекова
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Online Access:https://www.vestnik-grekova.ru/jour/article/view/324
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author D. E. Alekseev
D. V. Svistov
D. E. Matsko
E. D. Alekseev
author_facet D. E. Alekseev
D. V. Svistov
D. E. Matsko
E. D. Alekseev
author_sort D. E. Alekseev
collection DOAJ
description OBJECTIVE. The study investigated and compared the efficacy of plasty of dura mater using different collagen materials in the experiment. MATERIALS AND METHODS. The experimental study in vivo was carried out on 60 laboratory animals. Rabbits were divided into 4 groups after performing the craniotomy and dura mater opening. It depended on the material used for plasty of dural defects such as Duraform, Lyostypt and Russian prototype of collagen matrix for dural grafting. The fourth group was the control group. The presence and severity of meningo-cerebral adhesion, histological and immunological researches of duraplasty areas were performed after the experiment. RESULTS. The severity of meningo-cerebral adhesion was significantly higher in control group, but there wasn’t noted any meaningful difference in the groups with different collagen matrices. These groups had similar histological and immunohistochemical features. CONCLUSIONS. An application of collagen matrix improved the results of duraplasty and prevented formation of meningo-cerebral adhesions in the experiment. This data predict the high clinical efficacy of the method.
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institution Kabale University
issn 0042-4625
language Russian
publishDate 2017-04-01
publisher Pavlov First Saint Petersburg State Medical University
record_format Article
series Вестник хирургии имени И.И. Грекова
spelling doaj-art-fdea49e4fb2f4c4f93a933c4b17f6d2c2024-11-26T10:43:46ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252017-04-011762707610.24884/0042-4625-2017-176-2-70-76323PLASTY OF DURA MATER DEFECTS BY COLLAGEN IMPLANTS USING NON-SUTURE CONTACT DIRECT BONDING METHODD. E. Alekseev0D. V. Svistov1D. E. Matsko2E. D. Alekseev3S. M. Kirov Military Medical AcademyS. M. Kirov Military Medical AcademySt. Petersburg Clinical Research and Practical Centre of Specialized Types of Medical Care (Oncological)S. M. Kirov Military Medical AcademyOBJECTIVE. The study investigated and compared the efficacy of plasty of dura mater using different collagen materials in the experiment. MATERIALS AND METHODS. The experimental study in vivo was carried out on 60 laboratory animals. Rabbits were divided into 4 groups after performing the craniotomy and dura mater opening. It depended on the material used for plasty of dural defects such as Duraform, Lyostypt and Russian prototype of collagen matrix for dural grafting. The fourth group was the control group. The presence and severity of meningo-cerebral adhesion, histological and immunological researches of duraplasty areas were performed after the experiment. RESULTS. The severity of meningo-cerebral adhesion was significantly higher in control group, but there wasn’t noted any meaningful difference in the groups with different collagen matrices. These groups had similar histological and immunohistochemical features. CONCLUSIONS. An application of collagen matrix improved the results of duraplasty and prevented formation of meningo-cerebral adhesions in the experiment. This data predict the high clinical efficacy of the method.https://www.vestnik-grekova.ru/jour/article/view/324dura materdural substitutemeningo-cerebral adhesioncollagen matrix
spellingShingle D. E. Alekseev
D. V. Svistov
D. E. Matsko
E. D. Alekseev
PLASTY OF DURA MATER DEFECTS BY COLLAGEN IMPLANTS USING NON-SUTURE CONTACT DIRECT BONDING METHOD
Вестник хирургии имени И.И. Грекова
dura mater
dural substitute
meningo-cerebral adhesion
collagen matrix
title PLASTY OF DURA MATER DEFECTS BY COLLAGEN IMPLANTS USING NON-SUTURE CONTACT DIRECT BONDING METHOD
title_full PLASTY OF DURA MATER DEFECTS BY COLLAGEN IMPLANTS USING NON-SUTURE CONTACT DIRECT BONDING METHOD
title_fullStr PLASTY OF DURA MATER DEFECTS BY COLLAGEN IMPLANTS USING NON-SUTURE CONTACT DIRECT BONDING METHOD
title_full_unstemmed PLASTY OF DURA MATER DEFECTS BY COLLAGEN IMPLANTS USING NON-SUTURE CONTACT DIRECT BONDING METHOD
title_short PLASTY OF DURA MATER DEFECTS BY COLLAGEN IMPLANTS USING NON-SUTURE CONTACT DIRECT BONDING METHOD
title_sort plasty of dura mater defects by collagen implants using non suture contact direct bonding method
topic dura mater
dural substitute
meningo-cerebral adhesion
collagen matrix
url https://www.vestnik-grekova.ru/jour/article/view/324
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AT dvsvistov plastyofduramaterdefectsbycollagenimplantsusingnonsuturecontactdirectbondingmethod
AT dematsko plastyofduramaterdefectsbycollagenimplantsusingnonsuturecontactdirectbondingmethod
AT edalekseev plastyofduramaterdefectsbycollagenimplantsusingnonsuturecontactdirectbondingmethod