Identification of Nogo-B as a potential therapeutic target of osteosarcoma via stereochemically selective covalent probes

Abstract Osteosarcoma (OS) has been defined as one of the most intricate and formidable malignant bone tumors, and there has been no significant improvement in targeted therapies for OS over the past 50 years. Therefore, it is crucial to identify new potential drug targets for OS. Here, we have deve...

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Bibliographic Details
Main Authors: Jian Xue, Meng Li, Li Kang, Meiting Wang, Jiabin Yin, Donghui Sun, Yaqi Deng, Qinghua Wei, Jiemin Wong, Tong Zhu, Shunying Liu
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07765-z
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