Exploring the association between serotonin transporter promoter region methylation levels and depressive symptoms: a systematic review and multi-level meta-analysis

Abstract Depressive disorders result from complex interactions among genetic, epigenetic, and environmental factors. DNA methylation, a key epigenetic mechanism, is crucial in understanding depressive symptoms development. The serotonin transporter gene (5-HTT) and its polymorphisms, like 5-HTTLPR,...

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Bibliographic Details
Main Authors: F. Javelle, G. Dao, M. Ringleb, W. Pulverer, W. Bloch
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03356-w
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