Synthesis, cytotoxic screening and molecular docking, DFT calculation of novel furan-heterocyclic derivatives as insecticidal agents

Abstract The insecticidal furan-2-carbaldehyde thiosemicarbazone (1) as staring compound underwent a nucleophilic substitution reaction with different reagents, chloroacetyl chloride, chloroacetic acid. 1,4-dibromobutane-2,3-dione and also, with different activated reagents 2-cyanoacetohydrazide, ph...

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Bibliographic Details
Main Authors: Hager G. El-kasabi, Margret M. Girges, Samira A. Abd El-Salam, Ahmed E. Suliman, Ghada E. Abdel-Ghani
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-06248-7
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