Number of children and dementia risk: a causal mediation analysis using data from the HUNT study linked with national registries in Norway

Number of children and dementia risk: a causal mediation analysis using data from the HUNT study linked with national registries in Norway

Abstract Background Childlessness, as well as having a high number of children, has been reported to be associated with an elevated risk of dementia compared to having 2–3 children. The mechanisms underlying these relationships are not well understood and may be mediated by different midlife risk fa...

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Main Authors: Teferi Mekonnen, Vegard Skirbekk, Ekaterina Zotcheva, Bo Engdahl, Bernt Bratsberg, Astanand Jugessur, Catherine Bowen, Geir Selbæk, Hans-Peter Kohler, Jennifer R. Harris, Sarah E. Tom, Steinar Krokstad, Trine Holt Edwin, Yehani Wedatilake, Katrin Wolfova, Dana Kristjansson, Yaakov Stern, Asta Kristine Håberg, Bjørn Heine Strand
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Neurology
Subjects:
Dementia
Causal mediation analysis
Number of childern
Online Access:https://doi.org/10.1186/s12883-025-04044-4
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