N-acetylcysteine stimulates organelle malfunction in endometriotic cells via IFN-gamma signaling

N-acetylcysteine stimulates organelle malfunction in endometriotic cells via IFN-gamma signaling

Abstract Endometriosis is a chronic inflammatory gynecologic disease characterized by the abnormal implantation of endometrial tissue outside the uterus. The inflammatory microenvironment of endometriosis is dominated by highly migratory endometriotic cells, inflammatory cells, and cytokines. There...

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Bibliographic Details
Main Authors: Elif Karakoç, Sevil Oskay Halaçlı, Rumeysa Havvanur Hanelçi, Selda Ayhan, Cemil Can Eylem, Emirhan Nemutlu, Pergin Atilla
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Endometriosis
N-acetyl cysteine
IFN-ɣ
ER stress
Mitochondrial dysfunction
Metabolomics
Online Access:https://doi.org/10.1038/s41598-025-00195-z
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https://doi.org/10.1038/s41598-025-00195-z

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