Atractylenolide I ameliorated the growth and enzalutamide resistance of castration-resistant prostate cancer by targeting KIF15

Abstract Background Castration-resistant prostate cancer (CRPC) has been a major cause of tumor-associated death among men worldwide. The discovery of novel therapeutic medicines for CRPC remains imperative. Atractylenolide I (ATR-I), a prominent bioactive component from Atractylodes macrocephala, e...

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Bibliographic Details
Main Authors: Chenglin Han, Bin Yang, Yuxuan Deng, Peng Hu, Bintao Hu, Xiaming Liu, Tao Wang, Chengbao Li, Jihong Liu, Huixing Yuan
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Chinese Medicine
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Online Access:https://doi.org/10.1186/s13020-025-01086-1
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