Angiotensin II Promotes Osteocyte RANKL Expression via AT1R Activation

Angiotensin II Promotes Osteocyte RANKL Expression via AT1R Activation

<b>Background/Objective:</b> Osteocytes are the most abundant cell type in the skeleton, with key endocrine functions, particularly in regulating osteoblast and osteoclast activity to maintain bone quality. Angiotensin II (Ang II), a critical component of the renin–angiotensin–aldosteron...

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Bibliographic Details
Main Authors: Jiayi Ren, Aseel Marahleh, Jinghan Ma, Fumitoshi Ohori, Takahiro Noguchi, Ziqiu Fan, Jin Hu, Kohei Narita, Angyi Lin, Hideki Kitaura
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomedicines
Subjects:
angiotensin II
osteocyte
MLO-Y4
osteoclastogenesis
Online Access:https://www.mdpi.com/2227-9059/13/2/426
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