Immune checkpoint inhibitor-induced myocarditis and multiple adverse events with pre-existing rheumatoid arthritis: a case report and literature review

Immune checkpoint inhibitor-induced myocarditis and multiple adverse events with pre-existing rheumatoid arthritis: a case report and literature review

Immune checkpoint inhibitors (ICIs) can trigger immune-related adverse events (irAEs) and rheumatoid arthritis (RA) reactivation in cancer patients with pre-existing RA. Studies indicate RA reactivation occurs in approximately 50% of these patients, while new irAEs develop in 25–50% of ICI-treated p...

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Main Authors: Shion Kachi, Mirei Shirakashi, Takashi Nomizo, Mei Onishi, Eri Toda Kato, Tomomi W. Nobashi, Hideo Onizawa, Ryosuke Hiwa, Hideaki Tsuji, Shuji Akizuki, Ran Nakashima, Akira Onishi, Hajime Yoshifuji, Masao Tanaka, Kosaku Murakami, Akio Morinobu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-08-01
Series:Immunological Medicine
Subjects:
Rheumatoid arthritis
immune checkpoint inhibitors
immune-related adverse events
myocarditis
organizing pneumonia
Online Access:https://www.tandfonline.com/doi/10.1080/25785826.2025.2515688
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https://www.tandfonline.com/doi/10.1080/25785826.2025.2515688

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