New Target Genes for the Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Antitumour Activity: Perspectives from the Insulin Receptor

The insulin receptor (IR) plays a crucial role in mediating the metabolic and proliferative functions triggered by the peptide hormone insulin. There is considerable evidence that abnormalities in both IR expression and function may account for malignant transformation and tumour progression in some...

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Bibliographic Details
Main Authors: Daniela P. Foti, Francesco Paonessa, Eusebio Chiefari, Antonio Brunetti
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2009/571365
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