Protocol to discover actionable cancer vulnerabilities enabled by neomorph protein-protein interactions with the AVERON Notebook
Summary: While some tumor driver mutations inhibit existing protein-protein interactions (PPIs), others can create neomorph interactions (neoPPIs) not characteristic of the wild-type counterparts. Such tumor-specific neoPPIs may represent targets for therapeutic interventions. Here, we present a pro...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | STAR Protocols |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166724006063 |
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